The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications. Take tadalafil exactly as directed. It belongs to the drug class known as PDE5 inhibitors. Common ‘nitrate’ medications include: Isosorbide Mononitrate Isosorbide Dinitrate Nitroglycerine Aside from nitrates, most other blood pressure medications classes do not represent a significant risk. Interestingly, Cialis has been more linked to improved self-esteem and other psychological factors than the other PDE5 medications.You need a prescription for Cialis or its generic counterpart, Tadalafil. Both items are useful in the treatment of an enlarged prostate, erectile dysfunction, and benign prostatic .  · Cialis (tadalafil) is prescribed to treat erectile dysfunction and symptoms of benign prostatic hyperplasia. It comes as a tablet that’s taken as needed or once per . Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged .