Tadalafil works for these conditions by promoting muscle relaxation, which improves blood flow in PAH and urinary flow in BPH. This medicine is also used to treat erectile dysfunction and signs and symptoms of BPH. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. This is high blood pressure that occurs in the main artery that carries blood from the right side of the heart the ventricle to the lungs. You’ll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Other General Warnings Talk to your doctor if You are a known patient with heart problems. How Effective Is Cialis?heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Common tadalafil side effects may include: headache; flushing (warmth, redness, or tingly feeling); nausea, upset stomach; stuffy nose; or. muscle pain, back pain, pain in your arms, legs, or back. This is not a complete list of side. With Goodrx, the generic version of Cialis 20 mg (tadalafil) is about $9 for 10 tablets. The brand version is about $ How much is generic Cialis? expand_more. Tadalafil is the generic name for Cialis. If you are taking it daily, it . Cialis and generic tadalafil are available in four different strengths— mg, 5 mg, 10 mg and 20 mg—but which one should you take? If you’ve never tried Cialis .