Yes, ED pills can cause side effects. An erection results from an increase in blood flow to the penis. If approved, the provider will issue a prescription. You’ll also need to fill out a medical questionnaire with answers about your medical history, current medications, and lifestyle habits. You should also call your insurance company to see if they cover erectile dysfunction medications. Most erectile dysfunction medications belong to the drug class known as PDE5 inhibitors , which help relax the muscles and increase blood flow to allow for a full erection. Those with a history of blood pressure or heart issues, hormonal imbalances, mental health issues, and diabetes should consult their doctor before trying PDE5 inhibitors.Cialis is approved for the treatment of men who experience difficulty having and maintaining an erection (impotence). Generic Cialis Availability. Last updated on Cialis is a brand name of tadalafil, approved by the FDA in the following formulation(s): CIALIS (tadalafil – tablet;oral) Manufacturer: LILLY Approval date: November 21, Strength(s): 5MG, 10MG, 20MG ; Manufacturer: LILLY Approval date: January 7, Cialis is Food and Drug Administration (FDA) approved to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BHP). Generic tadalafil became more widely available after